Which combination of findings is most indicative of cystic fibrosis in a child with respiratory symptoms?

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Multiple Choice

Which combination of findings is most indicative of cystic fibrosis in a child with respiratory symptoms?

Explanation:
The key idea is that cystic fibrosis often shows a combination of lung problems and poor growth because it affects both the airways and the digestive system. A chronic productive cough reflects ongoing thick mucus and recurrent lung infections, while failure to thrive signals pancreatic insufficiency and fat malabsorption, which blunt weight gain. When these two features appear together in a child with respiratory symptoms, CF becomes the most likely diagnosis. Salty skin can be a clue due to high sweat chloride, but it isn’t as specific as having both chronic cough and growth failure.

The key idea is that cystic fibrosis often shows a combination of lung problems and poor growth because it affects both the airways and the digestive system. A chronic productive cough reflects ongoing thick mucus and recurrent lung infections, while failure to thrive signals pancreatic insufficiency and fat malabsorption, which blunt weight gain. When these two features appear together in a child with respiratory symptoms, CF becomes the most likely diagnosis. Salty skin can be a clue due to high sweat chloride, but it isn’t as specific as having both chronic cough and growth failure.

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